Protein name:
Integrin beta-2 ;
Alternative:
Complement receptor C3 subunit beta ;Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta ;
CD:
CD18 ;
Organism:
Pig (Sus scrofa).
General Annotation
Sub Unit:
Heterodimer of an alpha and a beta subunit. Beta-2 associates with either alpha-L, alpha-M, alpha-X or alpha-D. Interacts with COPS5 and RANBP9. Interacts with FGR.
Function:
Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrins alpha-M/beta-2 and alpha-X/beta-2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin alpha-X/beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin alpha-M/beta-2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin alpha-M/beta-2 is also a receptor for factor X. Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1.
Subcellular Location:
Membrane
Single-pass type I membrane protein
Protein Attributes:
50:
MLCRCSPLLL | LVGLLTLRSA | LSQECAKYKV | STCRDCIESG | PGCAWCQKLN |
100:
FSGQGEPDSV | RCDTREQLLA | KGCVADDIVD | PRSLAETQED | QAGGQKQLSP |
150:
QKVTLYLRPG | QAATFNVTFR | RAKGYPIDLY | YLMDLSYSML | DDLINVKKLG |
200:
GDLLRALNEI | TESGRIGFGS | FVDKTVLPFV | NTHPEKLRNP | CPNKEKECQA |
250:
PFAFRHVLKL | TDNSNQFQTE | VGKQLISGNL | DAPEGGLDAM | MQVAACPEEI |
300:
GWRNVTRLLV | FATDDGFHFA | GDGKLGAILT | PNDGRCHLED | NLYKSSNEFD |
350:
YPSVGQLAHK | LAESNIQPIF | AVTKKMVKTY | EKLTDIIPKS | AVGELSEDSS |
400:
NVLELIKNAY | NKLSSRVFLD | HNALPDTLKV | TYDSFCSNGV | SQVNQPRGDC |
450:
DGVQINVPIT | FQVKVTASEC | IQEQSFVIRA | LGFTDTVTVR | VLPQCECRCG |
500:
DSSKERTLCG | NKGSMECGVC | RCDAGYIGKH | CECQTQGRSS | QELEGSCRKD |
550:
NSSIICSGLG | DCICGQCVCH | TSDVPNKKIY | GQFCECDNMN | CERFDGQVCG |
600:
GEKRGLCFCS | TCRCQEGFEG | SACQCLKSTQ | GCLNLQGVEC | SGRGRCRCNV |
650:
CQCDFGYQPP | LCTDCPSCQV | PCARYAKCAE | CLKFDTGPFA | KNCSAECGTT |
700:
KLLPSRMSGR | KCNERDSEGC | WMTYFLVQRD | GRDNYDLHVE | ETRECVKGPN |
750:
IAAIVGGTVG | GVVLVGIFLL | VIWKVLTHLS | DLREYKRFEK | EKLKSQWNND |
769:
NPLFKSATTT | VMNPKFAER
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Pig
Bovine
Mouse
ELISA Kit for Pig Integrin beta-2
ELISA Kit for Pig Integrin beta-2
ELISA Kit for Pig Integrin beta-2
ELISA Kit for Pig Integrin beta-2
CLIA Kit for Pig Integrin beta-2
CLIA Kit for Pig Integrin beta-2
CLIA Kit for Pig Integrin beta-2
CLIA Kit for Pig Integrin beta-2
Polyclonal Antibody for Pig Integrin beta-2
Polyclonal Antibody for Pig Integrin beta-2
Polyclonal Antibody for Pig Integrin beta-2
Polyclonal Antibody for Pig Integrin beta-2
Monoclonal Antibody for Pig Integrin beta-2
Monoclonal Antibody for Pig Integrin beta-2
Monoclonal Antibody for Pig Integrin beta-2
Monoclonal Antibody for Pig Integrin beta-2
Protein for Pig Integrin beta-2
Protein for Pig Integrin beta-2
Protein for Pig Integrin beta-2
Protein for Pig Integrin beta-2
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
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Cited for : NUCLEOTIDE SEQUENCE [MRNA]