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Index > Protein center > ITGB2(Gene name) > Pig
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  • ITGB2 (Gene name),
  • Integrin beta-2 (Protein name ),  ITB2_PIG from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Gene name:
    ITGB2(CD18);
    Protein name:
    Integrin beta-2;
    Alternative:
    Complement receptor C3 subunit beta;Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta;
    CD:
    CD18;
    Organism:
    Pig (Sus scrofa). 
    General Annotation
    Sub Unit:
    Heterodimer of an alpha and a beta subunit. Beta-2 associates with either alpha-L, alpha-M, alpha-X or alpha-D. Interacts with COPS5 and RANBP9. Interacts with FGR.
    Function:
    Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrins alpha-M/beta-2 and alpha-X/beta-2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin alpha-X/beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin alpha-M/beta-2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin alpha-M/beta-2 is also a receptor for factor X. Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1.
    Subcellular Location:
    Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    769
    Sequence:
    50:
    MLCRCSPLLL | LVGLLTLRSA | LSQECAKYKV | STCRDCIESG | PGCAWCQKLN | 
    100:
    FSGQGEPDSV | RCDTREQLLA | KGCVADDIVD | PRSLAETQED | QAGGQKQLSP | 
    150:
    QKVTLYLRPG | QAATFNVTFR | RAKGYPIDLY | YLMDLSYSML | DDLINVKKLG | 
    200:
    GDLLRALNEI | TESGRIGFGS | FVDKTVLPFV | NTHPEKLRNP | CPNKEKECQA | 
    250:
    PFAFRHVLKL | TDNSNQFQTE | VGKQLISGNL | DAPEGGLDAM | MQVAACPEEI | 
    300:
    GWRNVTRLLV | FATDDGFHFA | GDGKLGAILT | PNDGRCHLED | NLYKSSNEFD | 
    350:
    YPSVGQLAHK | LAESNIQPIF | AVTKKMVKTY | EKLTDIIPKS | AVGELSEDSS | 
    400:
    NVLELIKNAY | NKLSSRVFLD | HNALPDTLKV | TYDSFCSNGV | SQVNQPRGDC | 
    450:
    DGVQINVPIT | FQVKVTASEC | IQEQSFVIRA | LGFTDTVTVR | VLPQCECRCG | 
    500:
    DSSKERTLCG | NKGSMECGVC | RCDAGYIGKH | CECQTQGRSS | QELEGSCRKD | 
    550:
    NSSIICSGLG | DCICGQCVCH | TSDVPNKKIY | GQFCECDNMN | CERFDGQVCG | 
    600:
    GEKRGLCFCS | TCRCQEGFEG | SACQCLKSTQ | GCLNLQGVEC | SGRGRCRCNV | 
    650:
    CQCDFGYQPP | LCTDCPSCQV | PCARYAKCAE | CLKFDTGPFA | KNCSAECGTT | 
    700:
    KLLPSRMSGR | KCNERDSEGC | WMTYFLVQRD | GRDNYDLHVE | ETRECVKGPN | 
    750:
    IAAIVGGTVG | GVVLVGIFLL | VIWKVLTHLS | DLREYKRFEK | EKLKSQWNND | 
    769:
    NPLFKSATTT | VMNPKFAER
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    UniGene:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Pig Integrin beta-2
    Cat.:
    E0236h
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Pig Integrin beta-2
    Cat.:
    E0236p
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Pig Integrin beta-2
    Cat.:
    E0236b
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    Packing:
    96T
    ELISA Kit for Pig Integrin beta-2
    Cat.:
    E0236m
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Pig Integrin beta-2
    Cat.:
    U0236b
    Price:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Pig Integrin beta-2
    Cat.:
    U0236m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Pig Integrin beta-2
    Cat.:
    U0236p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Pig Integrin beta-2
    Cat.:
    U0236h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Pig Integrin beta-2
    Polyclonal Antibody for Pig Integrin beta-2
    Cat.:
    P0236Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Pig Integrin beta-2
    Cat.:
    P0236Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Pig Integrin beta-2
    Monoclonal Antibody for Pig Integrin beta-2
    Monoclonal Antibody for Pig Integrin beta-2
    Monoclonal Antibody for Pig Integrin beta-2
    Monoclonal Antibody for Pig Integrin beta-2
    Protein for Pig Integrin beta-2
    Protein for Pig Integrin beta-2
    Protein for Pig Integrin beta-2
    Protein for Pig Integrin beta-2

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    References
    1. 1.
      "Molecular cloning and characterization of the porcine CD18 leukocyte adhesion molecule."
      Lee J.K. , Schook L.B. , Rutherford M.S.
      Xenotransplantation3:222-230(1996)
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
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